Determination of Phase-transition Temperature of White Vaseline Produced by Different Processes by DSC
- VernacularTitle:差示扫描量热法测定不同生产工艺的白凡士林相变温度
- Author:
Jing XIAO
1
;
Yang LIU
;
Yong ZHAO
;
Yingying XIE
;
Pujun ZENG
;
Haiyan LONG
Author Information
1. 湖南省药品检验研究院 长沙410001
- Keywords:
DSC;
White vaseline;
Phase-transition temperature;
Melting point;
Production process
- From:
China Pharmacist
2017;20(12):2169-2172
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the phase-transition temperature of white vaseline produced by different processes by differen-tial scanning calorimetry ( DSC) in order to analyze the relevance between the melting point and the phase-transition temperature and the relevance between different production processes and the phase-transition temperature. Methods: Hermertic aluminum pans were used to encapsulate the samples, and the testing conditions were optimized. The sample weight was about 10 mg, and the range of measuring temperature was -20-100℃. The heating rate was 5℃·min-1 and the flow rate of nitrogen was 30 ml·min-1 . Results:The phase-transition temperature and the melting point were significantly different. The phase-transition temperature of white vaseline samples produced by different processes was quite different. Conclusion:Melting point determination in the current standard method of white vaseline exists defects, and the composition of white vaseline produced by various processes is quite different.
