Rational Drug Use Analysis of Parkinson's Disease with the First Time Attack of Epilepsy
- VernacularTitle:帕金森病首发癫痫患者的合理用药分析
- Author:
Shaowei SUN
1
;
Chuanmei WEI
;
Zheng SONG
;
Minghua LIU
;
Peimin GAO
Author Information
1. 滨州医学院附属医院药学部 山东滨州256603
- Keywords:
Parkinson' s disease;
Epilepsy;
L-dopa induced dyskinesia;
Valproic acid
- From:
China Pharmacist
2017;20(12):2196-2198
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To bring to doctors' attention to the first time attack of epilepsy in the patients with Parkinson' s disease, enhance the rational drug use and reduce the occurrence of adverse reactions in clinics. Methods: A Parkinson patient with the first time attack of epilepsy was synthetically analyzed on the mechanism of disease, therapy regimen and pharmaceutical care. Results:It was difficult to distinguish the symptom of epilepsy during the treatment of Parkinson' s disease from that of L-dopa induced dyskinesia, therefore, the suitable treatment was difficult to perform. Moreover, antiepileptic drug valproic acid could aggravate Parkinson syn-drome imperceptibly, which was easy to be ignored in clinics. Conclusion:L-dopa induced dyskinesia should try to avoid during the treatment of Parkinson, and should distinguish from the first time attack of epilepsy in order to choose proper antiepileptic drugs.
