Association between enterohepatic circulation of bile acid and cholestatic liver disease
10.3969/j.issn.1001-5256.2017.10.014
- VernacularTitle:胆汁酸的肠肝循环与胆汁淤积性肝病
- Author:
Xiaofeng LI
1
;
Jingyu GONG
;
Jianshe WANG
Author Information
1. 复旦大学附属金山医院儿科
- Keywords:
cholic acid;
enterohepatic circulation;
cholestasis
- From:
Journal of Clinical Hepatology
2017;33(10):1922-1927
- CountryChina
- Language:Chinese
-
Abstract:
The development of cholestatic liver disease is closely associated with the enterohepatic circulation disorder of bile acid.This article elaborates on metabolism of bile acid,enterohepatic circulation-related mechanism of hereditary cholestasis,molecular regulation of related transporters,and association between current therapeutic regimens and enterohepatic circulation,in order to investigate the pathogenesis of cholestatic liver disease and provide a basis for the research on new drugs or therapies.
