The value of MR T2* in evaluation of liver iron overload related to long term blood transfusion
10.3969/j.issn.1002-1671.2017.12.014
- VernacularTitle:磁共振T2*在输血性铁过载肝脏铁沉积中的应用价值
- Author:
Jiajia XU
1
;
Li XIANG
;
Liwei ZOU
;
Lianzi SU
;
Yanqi SHAN
;
Suisheng ZHENG
;
Xijun GONG
Author Information
1. 安徽医科大学第二附属医院放射科
- Keywords:
liver;
magnetic resonance imaging;
T2*;
iron deposition
- From:
Journal of Practical Radiology
2017;33(12):1867-1869,1890
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of MR T2* in evaluation of liver iron overload caused by long term blood transfusion.Methods Thirty one patients with long term blood transfusion were collected.Both serum ferritin(SF)and CRP levels were measured and the adjusted serum ferritin(ASF)concentration was calculated.MRI of the maximum cross-sectional liver was performed using a 1.5T scanner (Siemens Avanto).The T2* value of the liver was measured,and the correlation analysis was carried out.Twenty one normal volunteers served as controls.The transfusion group was divided into iron overload group and non overload group,and differences between groups were analyzed.Results The correlation coefficient in 31 patients between liver T2* value and SF,ASF and blood transfusion volume was-0.695,-0.728 and -0.657 respectively,and the difference was statistically significant(P<0.05).The correlation coefficient between SF and blood transfusion volume was 0.518,and the difference was statistically significant(P<0.05).There was difference in T 2* value between three groups.Conclusion MR T2* has some practical value in the evaluation of liver iron overload in patients with long term blood transfusion.
