Clinical effect of polylactic acid membrane in the surgery of lumbar disc herniation
10.3760/cma.j.issn.1008-6315.2018.01.014
- VernacularTitle:防粘连膜在腰椎间盘突出症手术中应用的临床效果
- Author:
Yubao HE
1
;
Longxi REN
;
Jieying WANG
;
Bo LIU
Author Information
1. 100022,北京市垂杨柳医院骨科
- Keywords:
Anti-adhesion membrane;
Lumbar disc herniation;
Peridural scar
- From:
Clinical Medicine of China
2018;34(1):71-74
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether the polylactic acid(PLA)membrane can reduce the scar size and or improve the clinical outcome of the patients after lumbar disc herniation surgery,and the association between peridural scarring and recurrent pain after lumbar disc herniation surgery.Methods Seventy-two patients treated with lumbar disc herniation surgery were collected and randomly divided into two groups, including 38 cases were treated with PLA membrane,and 34 cases as the control group.All patients underwent MRI at 12 months after surgery for grading the size,location and development of the scar.NRS was used to assess the severity of lower limb pain before and 12 months after surgery.The modified Macnab scale was used to assess the clinical outcomes of the patients.Results For 9 cases(23.7%)in the PLA membrane group,the scar tissue had an effect on the nerve root,while 16 cases(47.1%)in the control group experienced the same,the difference was statistically sigificant(χ2=4.326,P=0.038).There was significant difference in scar score between the two groups(Z=2.340,P=0.019),but there was no significant difference in leg pain degree between the two groups(t=0.687,1.014,0.426,0.000,P=0.532,0.324,0.675,1.000).There was no significant difference between the two groups in modified Macnab classification grading(χ2=1.202,P=0.273).Conclusion PLA membranes used in lumbar disc herniation surgery could reduce peridural scar formation,but it does not significantly improve the clinical results.
