Mechanism of autophagy in the occurrence of cardiovascular disease
10.3760/cma.j.issn.1008-6315.2018.01.018
- VernacularTitle:自噬在心血管疾病发生发展中的作用机制
- Author:
Wenshuang ZHAO
1
;
Xiaoyu WU
Author Information
1. 150001,哈尔滨医科大学附属第一医院心内科
- Keywords:
Autophagy;
Cardiovascular disease;
Signaling pathways;
Mechanism
- From:
Clinical Medicine of China
2018;34(1):86-88
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular diseases is a kind of circulatory system disease,circulatory system mainly includes the heart and blood vessels,the common disease including myocardial ischemia,cardiomyopathy,heart failure,arrhythmia and sudden cardiac death.With the change of human living environment and habits, cardiovascular diseases has become the leading cause of human death[1].Autophagy is an important regulation method for the steady state of eukaryotic cells,which has been proved to be closely related to various diseases and is a hotspot in the research of human diseases in recent years.Autophagy is closely related to the occurrence of cardiovascular diseases,and plays an important role in the prevention and control of cardiovascular diseases, but the specific mechanism still needs to be further studied.This paper introduces the concept and mechanism of autophagy,and summarizes the mechanism of autophagy in cardiovascular disease.
