Comparison of analgesic effect of ropivacaine and bupivacaine in painless childbirth and effects on maternal stress response
10.7501/j.issn.1674-6376.2017.10.022
- VernacularTitle:罗哌卡因与布比卡因在无痛分娩中的镇痛效果及对产妇应激反应的影响
- Author:
Hao YANG
1
Author Information
1. 宝鸡市第五人民医院麻醉科
- Keywords:
labor analgesia;
ropivacaine;
bupivacaine;
stress response
- From:
Drug Evaluation Research
2017;40(10):1468-1471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate analgesic effect of ropivacaine and bupivacaine in painless childbirth and response to maternal stress.Methods The voluntary labor analgesia maternal 210 cases in The Fifth People's Hospital of Baoji City from June 2015 to December 2016 were randomly divided into A group and B group.105 cases collected during the same period to take maternal painless childbirth as the control group,A group was given ropivacaine combined with fentanyl anesthesia,B group received bupivacaine combined with fentanyl anesthesia,observe the analgesic effect and the effect on maternal stress response.Results The difference between the groups before anesthesia score VAS was not statistically significant.After anesthesia compared with before anesthesia,A group and B VAS scores were reduced,the control group increased,the difference was statistically significant (P ＜ 0.05).And VAS in A and B group was significantly lower than the control group,the difference was statistically significant (P ＜ 0.05).After evaluation,there was no statistical difference between the two groups in MBS score.1,5 min,Apgar scores were not statistically significant in the 3 groups.Compared with the 1 rain Apgar score,Apgar scores in 3 and 5 min were increased,the difference was statistically significant (P ＜ 0.05).Blood glucose levels in B group and control group were increased (P ＜ 0.05).Cortisol levels in group A and group B before anesthesia were higher than the control group (P ＜ 0.05);A~er anesthesia,cortisol levels in group B was higher than the control group,A group was lower than that in group B (P ＜ 0.05).Before anesthesia,the ratio of insulin/blood glucose in the A group and the B group was lower than that in the control group (P ＜ 0.05),and that in A group and B group afder anesthesia was higher than that in the control group,and the level of A group was lower than that of the B group (P ＜ 0.05).Conclusion maternal analgesia with patient-controlled infusion effect,and can reduce maternal stress reaction,it is worthy of recommendation.
