Three cases of dermatomyositis presenting with inverse Gottron's papules
10.3760/cma.j.issn.0412-4030.2017.12.004
- VernacularTitle:伴反向Gottron丘疹的皮肌炎三例
- Author:
Qiuxia MAO
1
,
2
;
南京中医药大学附属江阴医院江阴市中医院皮肤科,214400
;
Wanlu ZHANG
;
Wenrui LI
;
Sijia ZHAO
;
Jianfang SUN
;
Pan'gen CUI
;
Chengrang LI
Author Information
1. 210042南京,中国医学科学院北京协和医学院皮肤病医院皮肤科
2. 南京中医药大学附属江阴医院江阴市中医院皮肤科,214400
- Keywords:
Dermatomyositis;
Lung diseases,interstitial;
Inverse Gottron's papules
- From:
Chinese Journal of Dermatology
2017;50(12):875-878
- CountryChina
- Language:Chinese
-
Abstract:
Three cases of dermatomyositis presenting with inverse Gottron's papules were reported.Of the 3 patients,there were 2 males and 1 female aged 43,41 and 46 years respectively,whose disease durations were 1,6,7 months respectively.Inverse Gottron's papules manifested as papules overlying the palmar aspect of the metacarpal and interphalangeal joints,which were arranged in a linear pattern in 2 cases.Of the 3 cases,1 presented with interstitial pneumonia,3 with myositis,and 2 showed negative anti-nuclear antibody test.Histopathological examination of inverse Gottron's papules in 1 case revealed focal liquefaction degeneration of basal cells and perivascular infiltration with inflammatory cells,especially lymphocytes,in the superficial dermis.The 3 patients received oral glucocorticoids and immunosuppressive agents in the early period of treatment.After 3-month treatment,clinical symptoms including muscle weakness and muscle pain were improved evidently,but no obvious improvement in inverse Gottron's papules was observed.After 1-year treatment,these papules on the palmar aspect were markedly relieved in 1 case.
