Effect of needle arrangement on the lung dose in interstitial brachytherapy for lung cancer

VernacularTitle:肺癌插植放疗中插植针排列规则对肺受量影响研究
Author: Bo YANG ¹ ; Xiaoyang SUN ; Haowen PANG ; Xiangxiang SHI ; Guangpeng ZHANG ; Longjing TAN ; Renjin CHEN ; Tao TANG ; Hong WU ; Jingbo WU
Author Information

1. 西南医科大学附属医院肿瘤科
Keywords: Lung neoplasms/interstitial brachytherapy; Treatment planning system
From: Chinese Journal of Radiation Oncology 2017;26(12):1417-1420
CountryChina
Language:Chinese
Abstract: Objective To analyze the effect of needle arrangement on the lung dose in interstitial brachytherapy for lung cancer. Methods For 15 patients undergoing interstitial brachytherapy for lung cancer, a virtual radiotherapy plan in which needle arrangement was not restricted by the ribs was designed and compared with the original plan. For the two plans, V5, V20, V30, and mean lung dose(MLD)of the whole lung were determined when the prescribed doses were 10,30, 60, and 120 Gy, respectively. The data were analyzed by Wilcoxon signed-rank test. Results The lung V5,V20, V30, and MLD were significantly smaller in the virtual plan than in the actual plan(all P<0.05). Conclusions Irregular needle arrangement prevents a further reduction in the lung dose in interstitial brachytherapy for lung cancer. In the implantation surgery, therefore, the needles should be arranged as regularly as possible.