The inhibition of citral on platelet aggregation induced by arachidonic acid
10.3969/j.issn.1006-5725.2017.21.031
- VernacularTitle:柠檬醛对花生四烯酸诱导血小板聚集抑制效果的影响
- Author:
Weiqing HUANG
1
;
anyuan yu HUANG
;
Zongxia MOU
;
Baochang SU
Author Information
1. 暨南大学附属第一医院输血科
- Keywords:
citral;
plaelets;
arachidonic acid;
aggregation
- From:
The Journal of Practical Medicine
2017;33(21):3623-3627
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the effects of citral on adhesion and aggregation of platelets induced by AA(arachidonic acid)for clinical treatment and prevention of thrombotic diseases. Methods Evaluation of citral on adhesion and aggregation of platelets induced by AA were processed by multimode reader. Results There was significant difference in inhibiting aggregation of platelets between the control group and the drug group in a concen-tration of 111 μg/mL of citral.A series of concentration of citral also contributed the same effect in concentration of 25,30,35 mmol/L of AA. Conclusions The most effective concentration of citral is 111 μg/mL in inhibiting aggregation of platelets.The citral has an effect in inhibiting aggregation of platelets.