Effect of saxagliptin on peripheral blood neutrophil-to-lymphocyte ratio in elder patients with type 2 diabetes mellitus

VernacularTitle:沙格列汀对老年2型糖尿病中性粒细胞/淋巴细胞比值的影响
Author: Huilian HUA ¹ ; Chunzhi ZHAO ; Fangyong LOU
Author Information

1. 225300,泰州市人医院药剂科
Keywords: Saxagliptin; Diabetes mellitus; type 2; Neutrophil-to-lymphocyte ratio
From: Chinese Journal of Endocrinology and Metabolism 2017;33(11):959-961
CountryChina
Language:Chinese
Abstract: To explore the clinical effect of saxagliptin on release of peripheral blood neutrophil-to-lymphocyte ratio(NLR)in elder patients with type 2 diabetes mellitus. A total of 110 newly-diagnosed elder patients with type 2 diabetes were assigned into 2 groups(both n=55). Trial group was treated with exercise-diet therapy and saxagliptin at 5 mg/d(SG group),while control group with exercise-diet therapy and repaglinide(RG group). NLR were evaluated in both groups before treatment without significant difference(P>0.05). After 12 weeks'treatment, NLR were both lowered. Decrease of NLR in SG group was more significant than that of RG group(P<0.05).