Clinical features of tuberculosis in patients with systemic lupus erythematosus

VernacularTitle:系统性红斑狼疮合并结核的临床特征和相关因素分析
Author: Zhongping ZHAN ¹ ; Minxi LAO ; Fan SU ; Dongying CHEN ; Liuqin LIANG ; Xiuyan YANG
Author Information

1. 中山大学附属第一医院风湿免疫科
Keywords: systemic lupus erythematosus; mycobacterium tuberculosis; pulmonary tuberculosis; extra-pulmonary tuberculosis
From: The Journal of Practical Medicine 2017;33(21):3552-3555
CountryChina
Language:Chinese
Abstract: Objective To describe the characteristics and risk factors for Mycobacterium tuberculosis (TB)infection in patients with systemic lupus erythematosus(SLE).Methods A retrospective analysis was per-formed. Results Among our sample of 784 hospitalized patients,42(5.4%)were diagnosed with TB infection. Seventeen were pulmonary TB,11 were pulmonary and extra-pulmonary TB and 14 were extra-pulmonary TB.hest X-rays showed Abnormal chest imaging was observed in 34 cases,among which,19 were multi-lobar involvements and 9 were single-lobe involvements. Logistic regression multivariate analysis indicated that anemia and the daily mean dose of glucocorticoid(GC)were associated with TB. Conclusions Manifestations of TB in SLE patients were atypical.Anemia and the daily mean dose of GC were associated with TB.