Correlation between plasma NT-proBNP level and the severity of acute asthmatic attack

VernacularTitle:血浆NT-proBNP与哮喘急性发作严重程度的相关性
Author: Zhanqing ZHAO ¹ ; Chengcun WANG ; Xiaomin ZHOU ; Zhenyu LAI ; Chuan LI
Author Information

1. 海南西部中心医院重症医学科
Keywords: NT-proBNP; acute asthmatic attack; APACHEⅡ; PEF
From: The Journal of Practical Medicine 2017;33(21):3570-3573
CountryChina
Language:Chinese
Abstract: Objective To investigate the relationship between the plasma NT-proBNP level and the severity of acute asthmatic attack,and to provide a reference for the assessment of the severity of asthma and the prognosis of patients with acute asthmatic attack. Methods A total of 103 adult patients with mild,moderate,severe,and very severe acute asthmatic attack were enrolled in this study. The difference of plasma NT-proBNP level among groups,and the correlation between plasma NT-proBNP level and APACHE II score(Acute Physiology and Chron-ic Health Evaluation)were investigated.The correlation between plasma NT-proBNP level and Peak Expiratory Flow (PEF)was also studied in each group. Results There was significant difference in plasma NT-proBNP among groups(P < 0.05). Plasma NT-proBNP and APACHE II score was positive correlated(R = 0.767 1,P < 0.05). However,plasma NT-proBNP was negatively correlated with PEF(R =-0.709 7,P < 0.05). Conclusion NT-proBNP can be used as one of the indexes to evaluate the severity of acute asthmatic attack.