GRACE Score on Prognosis of ST-segment Elevation Myocardial Infarction in Patients Elder Than 75 Years With Primary Percutaneous Coronary Intervention
10.3969/j.issn.1000-3614.2017.12.005
- VernacularTitle:GRACE评分对75岁以上急性ST段抬高型心肌梗死患者直接经皮冠状动脉介入治疗预后的分析
- Author:
dong Shao YE
1
;
Lin LI
;
jia Si WANG
;
wei Zhong SUN
;
Hong QIU
;
ying Xiao HU
;
Lei FENG
;
wei Chao MU
;
jin Yue YANG
;
jian Yong WU
Author Information
1. 中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 心内科
- Keywords:
Myocardial infarction;
Aged;
Angioplasty;
transluminal;
percutaneous coronary;
GRACE score
- From:
Chinese Circulation Journal
2017;32(12):1163-1166
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore GRACE (global registry of acute coronary events)score on short term prognosis of ST-segment elevation myocardial infarction (STEMI)in patients elder than 75 years with primary percutaneous coronary intervention(PCI). Methods: A total of 104 STEMI patients elder than 75 years with primary PCI in our hospital from 2011-11 to 2014-01 were studied. Based on GRACEscore at admission, the patients were divided into 2 groups: Lower/mid risk group, n=72 patients with GRACEscore at 112-154 (136.5±10.6) and High risk group, n=32 patients with GRACE score at 155-202(167.8±12.3). The baseline condition and outcomes were compared between 2 groups and the primary endpoint was 1 year mortality. Predictive value of GRACEscore on 1 year mortality was evaluated by ROC curve, the relationships between Lower/mid risk group, High risk group and clinical outcomes were assessed by log-ranksurvive curve andunivariate Cox regression analysis. Results: The area under ROC curve for GRACEscore predicting 1 year mortality was 0.788 with the sensitivity at 70.0%and specificity at 84.0 %.Univariate Cox regression analysis indicated that compared with Lower/mid risk group, High risk group had the higher risk of 1-year death (HR=5.75, 95% CI 1.486-22.256, P=0.0113); log-rank survive curve presented that High risk group had the higher 1 year mortality (21.9% vs 4.2%, P=0.0039). Conclusion: GRACE score may further distinguish the lower/mid risk and high risk populations in elder STEMI patients; it may also predict 1 year clinical prognosis.
