Research progress of leosimendan for treatment of septic shock

VernacularTitle:左西孟旦治疗脓毒性休克的研究进展
Author: Caixia XU ¹ ; Li LI ; Jing YAN
Author Information

1. 浙江中医药大学第二临床医学院
Keywords: Shock; sepsis; Levosimendan; Internal organ functions; Haemodynamics
From: Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2017;24(6):669-672
CountryChina
Language:Chinese
Abstract: Sepsis is defined as a host imbalance of response induced by infection leading to life-threatening organ dysfunction, and septic shock is the most severe form of sepsis resulting from systemic circulatory and metabolic abnormalities, having high mortality rate. During septic shock stage, there are myocardial injury and myocardial inhibition, and after septic shock combined with cardiac injury, the mortality will be increased significantly. Levosimendan can improve cardiac function, hemodynamics, microcirculation, tissue oxygen metabolism, organ functions, etc in patients with septic shock. Now the effects of levosimendan on internal organ functions and hemodynamics in treatment of patients with septic shock are reviewed.