Community-acquired bacteria bloodstream sepsis in children:Analysis of pathogens and clinical characteristics in PICU
10.3760/cma.j.issn.1673-4912.2017.11.009
- VernacularTitle:PICU社区获得性细菌性血流感染病原分布及临床特点分析
- Author:
Tao ZHANG
1
;
Chunfeng LIU
;
Jiujun LI
;
Xiaoshi ZHENG
Author Information
1. 中国医科大学附属盛京医院 PICU
- Keywords:
Community-acquired bacteria bloodstream infection;
Children;
Mortality
- From:
Chinese Pediatric Emergency Medicine
2017;24(11):837-841
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between pathogen and disease characteristics of community-acquired bacterial bloodstream sepsis in PICU.Methods The clinical data of children diagnosed as sepsis admitted to the PICU of Shengjing Hospital of China Medical University between June 2011 and June 2016 were retrospectively analyzed.Medical records were screened to confirm the diagnosis of commu-nity-acquired bacteria bloodstream sepsis.Results One hundred and ninety-one children(108 males and 83 females) had confirmed community-acquired bacteria bloodstream sepsis with the following characteristics:167 patients(87.4%) with the age less than 36 months,50 patients(26.2%) with co-existing disease,40 pa-tients(20.9%) with shock,of which 33 patients had septic shock,and 41 patients(21.5%) died.Gram-posi-tive bacteria was the predominant pathogen(73.3%,140/191).Streptococcus pneumoniae was the primary pathogen(19.9%,38/140). Conclusion Community-acquired bacteria bloodstream sepsis in PICU most commonly affects children less than 36 months of age.Gram-positive bacteria are the predominant pathogenic bacteria,the most common pathogens are Streptococcus pneumoniae,Staphylococcus epidermidis,Staphylo-coccus aureus,Streptococcus pyogenes and Escherichia coli.The highest mortality rate in septic children is caused by Pseudomonas aeruginosa.Children with co-existing disease,sepsis complicated with shock and pa-tients requiring mechanical ventilation are risk factors for death.
