Application of endorectal elastography to evaluate local advanced rectal cancer after neoadjuvant radiochemotherapy:compared with pathology
10.3760/cma.j.issn.1004-4477.2017.10.013
- VernacularTitle:经直肠腔内超声弹性成像在局部进展期直肠癌新辅助放化疗后的应用研究:与病理对照
- Author:
Yue CONG
1
;
Shengri LIAO
;
Zhihui FAN
;
Zhongyi ZHANG
;
Rongjie LI
;
Kun YAN
Author Information
1. 100142,北京大学肿瘤医院暨北京市肿瘤防治研究所超声科 恶性肿瘤发病机制及转化研究教育部重点实验室
- Keywords:
Endosonography;
Elasticity Imaging Techniques;
Rectal Neoplasms;
Neoadjuvant Radiochemotherapy;
NCCN Tumor Regression Grade
- From:
Chinese Journal of Ultrasonography
2017;26(10):882-886
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of endorectal elastography with strain ratio to estimate local advanced rectal cancer after neoadjuvant radiochemotherapy.Methods In a retrospective study, endorectal ultrasound,endorectal elastography and enhanced rectal MRI were performed in 67 patients with local advanced rectal cancer after neoadjuvant radiochemotherapy.The imaging results were compared with postoperative pathological T stage and NCCN TRG.Results There was no significant difference in the diagnosis accuracy between T stage of ERUS(55.2%)and MRI(56.7%).Endorectal elastography results showed lesions confined to the rectal wall(T0-2 stage)were softer than lesions invaded the peripheral fat (T3)and the difference was statistically significant(P <0.05).When the cut-off point was set at SR<2.78,the sensitivity,specificity and accuracy of diagnosis of T0-2 were 64.7%,87.5% and 70.1% respectively.The lesion tended to have a greater SR value when residual tumor components increased(a higher NCCN TRG).Conclusions Endorectal elastography is an useful and effective imaging method to evaluate local advanced rectal cancer after neoadj uvant radiochemotherapy.It can help ERUS and rectal MRI to evaluate the lesions.
