Preparation and Application of Porous Layer Open Tubular Capillary Columns with Narrow Bore in Liquid Chromatography
10.11895/j.issn.0253-3820.171311
- VernacularTitle:窄内径多孔层开管柱的制备及在液相色谱中的应用
- Author:
Nan Ruo LI
1
;
Nan Ya WANG
;
Hua Man PENG
;
Yan Xia WANG
;
Sheng Guang GUO
Author Information
1. 绿色催化与分离北京市重点实验室
- Keywords:
Narrow bore;
Porous layer open tubular capillary columns;
Liquid chromatography;
Review
- From:
Chinese Journal of Analytical Chemistry
2017;45(12):1865-1873
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, micro/nano-scaled separation technique has attracted increasing attention due to its inherent advantages. The porous layer open tubular ( PLOT) capillary column is an important microcolumn form. Comparied to wide-bore PLOT capillary columns ( inner diameter >25 μm ) , the PLOT capillary columns with a narrow inner diameter yield higher separation efficiency and lower reagent consumption. In this paper, the preparation methods for porous layer open tubular capillary columns with narrow inner diameter, less than or equal to 25 μm, are reviewed. Detection techniques combined with mass spectrometry and their applications in liquid chromatography are also disussed.
