Study of the changing of right atrial volume and phasic function and its clinical value in patients with pulmonary hypertension
10.3760/cma.j.issn.1004-4477.2017.10.001
- VernacularTitle:肺动脉高压患者右心房容积和时相功能变化及其临床价值的研究
- Author:
Xiangli MENG
1
;
Yidan LI
;
Hong LI
;
Xiuzhang LYU
Author Information
1. 首都医科大学附属北京朝阳医院心脏超声科
- Keywords:
Echocardiography,three-dimensional;
Hypertension,pulmonary;
Atrial function,right
- From:
Chinese Journal of Ultrasonography
2017;26(10):829-833
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the right atrial(RA)volume and phasic function using three-dimensional echocardiography(3DE),and to examine the clinical relevance in pulmonary hypertension(PH). Methods Fifty PH patients and 20 control subjects were studied.RA volume,including maximum RA volume(Vmax),minimum RA volume(Vmin)and the volume before active systolic(Vpre-A)were evaluated by 3DE.RA maximum volume index(VmaxI),total emptying volume index(TotEVI),passive emptying volume index(PassEVI)and active ejection fraction(ActEF)were calculated.The correlation between RAVmaxI and the parameters of RV structure,function,pulmonary hemodynamics were analyzed.Results Maximum RA volume index(RAVmaxI)was higher in WHO functional class(WHO-FC)Ⅲ,Ⅳ of PH patients than in controls(all P <0.01).TotEVI was significantly higher in PH patients than in controls (P<0.001),but PassEVI was lower in PH patients than in controls(P =0.01 1).ActEF was similar when comparing PH patients of WHO-FC Ⅱ with controls.ActEF increased in PH patients with WHO-FCⅢ as compared with controls(P =0.008)but reduced in advanced with WHO-FC Ⅳ patients(P <0.001).RAVmaxI correlated with the indices of right ventricular(RV)structure,function and RV cardiac output index(all P <0.05).Conclusions PH is associated with increased RA size,increased TotEVI,and decreased PassEVI.ActEF increases in PH patients with WHO-FC Ⅲ but decreases in patients with WHO-FCⅣ.RA systolic function plays an important role in compensating RV dysfunction.