Detection and Drug Resistance of Mycoplasma in Vaginal Secretions of Gynecological Patients in Xi'an
10.3969/j.issn.1671-7414.2017.06.034
- VernacularTitle:西安地区妇科患者阴道分泌物支原体检测及耐药性分析
- Author:
Juan XIE
1
;
kang Wen LIU
;
Bo LI
;
Yun FAN
;
nan Hong CHEN
;
Ling LI
Author Information
1. 陕西省人民医院检验科
- Keywords:
vaginal secretion;
ureaplasma urealyticum;
mycoplasma hominis;
drug sensitivity test
- From:
Journal of Modern Laboratory Medicine
2017;32(6):118-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the infection and drug sensitivity of ureaplasma urealyticum(Uu)and mycoplasma hominis (Mh)in vaginal secretion of gynecological outpatients.Methods The infection and drug sensitivity test of Uu and Mh in va-ginal secretion samples of 1 800 patients collected from January 2015 to April 2016 were detected with mycoplasma culture i-dentification and counting drug sensitivity kit produced by Zhengzhou Antu Luke Bioengineering Co.,Ltd.Results The positive rate of Uu(57.27%)was significantly higher than that of Mh(2.78%,χ2=33.69,P<0.001).The positive rate of mycoplasma was highest in the age group of 31~35(77.09%),but that of Uu was highest in the age group of 21~25 (65.83%)and that of Mh in 36~40 years old group(9.09%),in addition that of multiple infection by Uu and Mh was highest in less than 20 years old group(20.51%).There were statistical difference for Un,Mh and co-infection by Un and Mh between age groups(χ2=15.505~36.574,P<0.01).The top three drugs sensitive for mycoplasma were josamycin, minocycline and doxycycline and that last three ones were clindamycin,thiamphenicol and sparfloxacin.The drug sensitive rates for 12 antibiotics against Uu were higher than those against co-infection by Uu and Mh,but those of erythromycin,gat-ifloxacin,azithromycin,clarithromycin and Luo Hongmei against Mh were lower than those against co-infecion of Uu and Mh.Conclusion The detection of mycoplasma and drug sensitivity in vaginal secretions provides the experimental basis for clinical diagnosis and treatment.
