Advances in the treatment of nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2017.12.041
- VernacularTitle:非酒精性脂肪性肝病的洽疗进展
- Author:
Gong FENG
1
;
Chunyan NIU
Author Information
1. 西安医学院
- Keywords:
nonalcoholic fatty liver disease;
therapy;
review
- From:
Journal of Clinical Hepatology
2017;33(12):2433-2438
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD)has become a major liver disease in the world and its prevalence rate continues to in-crease. As a component of metabolic syndrome,it has become a risk factor for many serious cerebrovascular and cardiovascular diseases. Due to the complex pathogenesis of NAFLD or the combined/ mutual effect of pathogenic factors,there are still no widely accepted effective therapies. In recent years,more and more studies have revealed new pathogeneses of NAFLD and the prospects of corresponding treatment. This article introduces the recent advances in the treatment of NAFLD,including lifestyle intervention,drug therapy,integrated traditional Chinese and Western medicine therapy,and bariatric surgery. In the aspect of drug therapy,this article introduces the drugs commonly used in clinical practice and new drugs in phase Ⅱ and Ⅲ clinical trials and their therapeutic effects.