Value of procalcitonin and high sensitivity C reactive protein detection in diagnosing hyperbilirubinemia premature infant complicating infection
10.3969/j.issn.1673-4130.2017.22.004
- VernacularTitle:降钙素原与超敏C反应蛋白检测在高胆红素血症早产儿合并感染诊断中的价值
- Author:
Qing LI
1
;
Ying CHEN
;
Min WANG
;
Meijuan ZHANG
;
Shengfeng QIU
Author Information
1. 南京医科大学第一附属医院检验学部
- Keywords:
procalcitonin;
high sensitivity C reactive protein;
hyperbilirubinemia;
premature infant
- From:
International Journal of Laboratory Medicine
2017;38(22):3083-3084,3087
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of procalcitonin (PCT ) and high sensitive C reactive protein (Hs-CRP) in the diagnosis of hyperbilirubinemia premature infant complicating infection .Methods A total of 192 cases of hyperbilirubinemia premature infants in our hospital were selected as the research subjects and divided into the infection group and non-infection group ac-cording to the clinical diagnostic results .The levels of WBC ,Hs-CRP ,PCT and total bilirubin(TB) were measured and performed the comparative analysis .Results The Hs-CRP ,PCT and TB levels in the infection group were significantly higher than those in the non-infected group ,the difference was statistically significant (P<0 .05);while there was no significant difference in WBC count between the two groups(P>0 .05) .PCT had higher sensitivity and specificity than Hs-CRP in the diagnosis of infection .The positive rates of PCT and Hs-CRP in the infection group were significantly higher than those in the non-infection group ,the difference was statistically significant (P<0 .05) .Conclusion PCT and Hs-CRP can guide the early diagnosis of hyperbilirubinemia premature infant complicating infection and are conducive to early treatment and rehabilitation of the neonatal patients .