Biodegradable microneedles applied in the transdermal drug delivery:research advances

VernacularTitle:生物可降解经皮给药微针研究进展
Author: feng Qian HUANG ¹ ; qing Hua LIN ; xin Bin PENG ; zhou Fang SHUAI
Author Information

1. 广东药科大学广东省药物新剂型重点实验室
Keywords: microneedle; biodegradable material; transdermal drug delivery
From: Journal of International Pharmaceutical Research 2017;44(8):778-782
CountryChina
Language:Chinese
Abstract: Microneedle is a painless and minimally invasive transdermal drug delivery. It can enhance the permeability of skin for macromolecular drugs by puncturing and creating a micron-level drug delivery channel in the skin. The biodegradable microneedles aim to solve the problem that nondegradable-material microneedles may break under skin and cause adverse reaction. This article pro?vides an overview of the characteristics of biodegradable microneedles,the biodegradable materials used,its recent research progress, the development status and the tendency.