Study of sex hormones and thyroid hormones in patients with macroprolactinemia
10.3969/j.issn.1673-4130.2017.22.009
- VernacularTitle:巨泌乳素血症患者血清性激素和甲状腺激素水平研究
- Author:
Qing LI
1
;
Shule WANG
;
Zhibin ZHANG
Author Information
1. 无锡市中医医院中心实验室
- Keywords:
macroprolactinemia;
hyperprolactinemia;
sex hormone;
thyroid hormone;
endocrine hormone
- From:
International Journal of Laboratory Medicine
2017;38(22):3097-3098,3101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the possible mechanism of in vivo production and congregation of macroprolactinemia (M-PRL) . Methods 50 cases of hyperprolactinemia(HPRL) ,50 cases of M-PRL and 25 healthy persons were selected as the HPRL group , M-PRL group and control group respectively .The chemiluminescence method was adopted to detect the levels of serum hormones and thyroid hormones .Then the detection results were statistically analyzed .Results The levels of serum testosterone ,sex hormone binding globulin(SHBG) ,thyroglobulin antibody and thyroid peroxidase in the M-PRL and HPRL groups were significantly higher than those in the control group .Serum estradiol levels in the M-PRL and HPRL group were lower than those in control group ,the difference was statistically significant (P＜0 .05) .Serum Prog level of the M-PRL group was lower than that of the control group ,the difference was statistically significant (P＜0 .05) .However the levels of serum testosterone ,estradiol ,luteinizing hormone(LH) ,follicle-stimulating hormone(FSH) and SHBG ,and LH/FSH ratio had no statistical difference between the M-PRL group and HPRL group(P＞0 .05) .Conclusion Certain degrees of sex hormones abnormality and autoimmune abnormality may exist in the patients with M-PRL .
