Clinical analysis of early application of nimodipine combined with lumbar cistern drainage in the treatment of severe traumatic brain injury
10.3969/j.issn.1673-4130.2017.22.010
- VernacularTitle:早期应用尼莫地平联合腰大池引流治疗重型颅脑损伤的临床分析
- Author:
Xiaoping RAN
1
Author Information
1. 资阳市人民医院普外一科
- Keywords:
lumbar cistern drainage;
severe traumatic brain injury;
intracranial infection
- From:
International Journal of Laboratory Medicine
2017;38(22):3099-3101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of early application of nimodipine combined with lumbar cistern drainage in the treatment of severe traumatic brain injury .Methods a total of 68 cases elderly patients with severe craniocerebral injury in our hospital from 2015 to 2017 were selected ,which were divided into control group and observation group according to random number table method .The control group was given routine medical treatment ,and the observation group was given nimodipine combined with lumbar cistern drainage on the basis of the control group .The Glasgow Coma Scale (GCS) score ,cerebral CT and blood flow velocity measurement of middle cerebral artery (MCA) were was performed ,and the recovery and prognosis were compared in the two groups .Results The GOS score and MCA blood flow velocity of the observation group at 7 ,14 and 21d after treatment were significantly higher than those in the control group(P＜0 .05);the decline rate of intracranial pressure in the observation group at 7 ,10 and 14d after treatment was significantly higher than that in the control group (P＜0 .05);the probability of infection in the observation group was significantly lower than that in the control group (P＜0 .05);the prognosis rate of the observation group was significantly better than that of the control group(P＜0 .01) .Conclusion Early use of nimodipine combined with lumbar continuous drainage in the treatment of severe traumatic brain injury can effectively improve the clearance rate of subarachnoid hemorrhage ,re-duce the occurrence of secondary brain injury ,avoid cerebral vasospasm ,and improve the prognosis of patients.
