Effects of bronchofibroscopic bronchoalveolar lavage on serum inflammatory cytokines levels in patients with severe ventilator-associated pneumonia
10.3969/j.issn.1673-4130.2017.22.006
- VernacularTitle:纤维支气管镜肺泡灌洗对重症呼吸机相关性肺炎患者血清炎症因子水平的影响
- Author:
Rongqin LI
1
;
Linqiao LIU
;
Tianfeng WU
;
Xiuying ZHOU
Author Information
1. 重庆医科大学附属第一医院綦江医院/重庆市綦江区人民医院感染管理科
- Keywords:
bronchofibroscopy;
alveolar lavage;
ventilator-associated pneumonia;
inflammatory factor
- From:
International Journal of Laboratory Medicine
2017;38(22):3088-3090
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of bronchofibroscopic bronchoalveolar lavage on serum inflammatory cytokines in the patients with severe ventilator-associated pneumonia(VAP) .Methods 68 cases of severe VAP were divided into the control group and observation group according to the random number table method ,34 cases in each group .The control group used conventional alveolar lavage plus sputum suction treatment ,while the observation group adopted bronchofibroscopic bronchoalveolar lavage plus sputum suction treatment .The lung infection control time ,mechanical ventilation treatment time ,time of body temperature recovery to normal ,pulmonary infection score(CPIS) ,white blood cell(WBC) count ,respiratory function ,blood gas indexes and serum inflammatory factors levels were compared between the two groups .Results The lung infection control time ,mechanical ventilation treatment time ,recovery time of normal temperature ,blood gas indexes and serum inflammatory factors levels after treatment in the observation group were significantly superior to those in the control group (P＜0 .05) .Conclusion Bronchofibroscopic bronchoalveolar lavage can significantly improve the respiratory function and blood gas indexes ,reduces the serum inflammatory factors levels in the patients with severe VAP .
