Efficacy and prognostic factors of arterial switch operation in patients with complete transposition of great arteries
10.3760/cma.j.issn.1008-1372.2017.11.021
- VernacularTitle:大动脉调转术治疗完全性大动脉转位患儿的疗效及预后影响因素分析
- Author:
Baoguo ZHOU
1
;
Zhaodong WANG
;
Lijun WANG
;
Zhenqian LV
;
Chenchen CHENG
Author Information
1. 青岛阜外心血管病医院心脏外科
- Keywords:
Transposition of great vessels/SU;
Prognosis
- From:
Journal of Chinese Physician
2017;19(11):1684-1687
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy and influencing factors of arterial switch operation (ASO) in the treatment of complete transposition of great arteries (TGA).Methods Totally 156 children with TGA who underwent ASO surgery from January 2005 to December 2011 were selected as the subjects.The clinical curative effect and prognosis of all patients were observed,and the relationship be tween clinical features and prognosis was analyzed.Results Totally 156 cases of TGA children were successfully completed the operation,and 29 patients died during the 5 year follow-up period,the mortality rate was 18.59％.Univariate analysis showed that the death in children with TGA after ASO was closely related to coronary artery abnormality,cardiopulmonary bypass time,aortic occlusion time,postoperative low cardiac output syndrome and reoperation (P ＜ 0.05).Multivariate logistic regression analysis showed that coronary artery abnormalities,and low cardiac output syndrome were independent outcome factors leading to postoperative death in patients.Conclusions The postoperative death of ASO in TGA children is closely related to the incidence of coronary artery abnormalities,the time of cardiopulmonary bypass,the time of oc clusion of aorta and the occurrence of postoperative low cardiac output syndrome,which should be pay attention to and take relevant measures.
