Research progress on the therapy of T-cell prolymphocytic leukemia
10.3969/j.issn.1000-8179.2017.21.610
- VernacularTitle:T-细胞幼淋巴细胞白血病治疗的研究进展
- Author:
DU YUNYUN
1
Author Information
1. 云南省第一人民医院血液科 昆明市650000
- Keywords:
T-cell prolymphocytic leukemia;
epigenetic;
therapy;
alemtuzumab;
stem cell transplantation
- From:
Chinese Journal of Clinical Oncology
2017;44(21):1108-1111
- CountryChina
- Language:Chinese
-
Abstract:
Prolymphocytic leukemia is a rare disease with typical characteristics, including aggressive progression and high mortality rate, and T-cell prolymphocytic leukemia (T-PLL) is regarded as an intractable subtype. Current therapeutic approaches mainly aim to improve their efficacy and remission against this disease. This paper presents a review about the research progress on T-PLL therapies. With remarkable research progress on leukemia pathogenesis, therapies for T-PLL have been greatly enhanced. Among treatment strategies, epigenetic therapy shows potential for clinical applications.
