Clinical research of Zhuanggu-Huoxue-Buyang decoction combined with negative pressure seal flushing drainage treatment for traumatic osteomyelitis
10.3760/cma.j.issn.1673-4246.2017.12.009
- VernacularTitle:自拟壮骨活血补阳汤联合负压封闭冲洗引流治疗创伤性骨髓炎临床研究
- Author:
Wenjie WU
1
;
Shujiang LIU
;
Zhiqiang LI
Author Information
1. 061000,河北省沧州市人民医院医专院区骨科
- Keywords:
Osteomyelitis;
Chronic disease;
Zhuanggu-Huoxue-Buyang decoction;
Negative-pressure wound therapy;
Drainage
- From:
International Journal of Traditional Chinese Medicine
2017;39(12):1090-1093
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical curative effect of Zhuanggu-Huoxue-Buyang decoction combined with negative pressure seal flushing drainage treatment for traumatic osteomyelitis. Methods According to the random number method, 132 patients with traumatic marrow from June 2015 to June 2016 in our hospital were divided into the control group and research group with 66 cases in each group. The patients of control group were treated with negative pressure seal flushing drainage, and the patients of research group were given to Zhuanggu-Huoxue-Buyang decoction on the basis of control group.Both groups were treated for 15 days. The clinical effective rate and clinically relevant indicators were counted, which included fracture healing time, granulation, covering time, average length of hospital stay, antibiotic use time, the negative pressure drainage time and positive rate of bacteria. At the same time patients complications were observed during the treatment. In addition, the recurrence rate of two groups was in the following half a year.Results The clinical effective rate of patients in the research group [95.5% (63/66) vs. 83.3% (55/66), χ2=5.114]was significantly higher than control group(P<0.05).The fracture healing time of patients in research group(5.3 ±1.1 months vs.7.6 ±1.9 months,t=-8.705)was significantly lower than the control group(P<0.05). The granulation covering time of patients in research group (27.8 ± 5.6 d vs.35.1 ± 6.4 d,t=-6.961) was significantly lower than the control group (P<0.05). The average length of hospital stay of patients in research group (31.2 ± 4.3 d vs.39.2 ± 5.1 d,t=-9.870) was significantly lower than the control group (P<0.05). The antibiotic use time of patients in research group(8.9 ±2.0 d vs.13.3 ±3.9 d,t=-8.152)was significantly lower than the control group (P<0.05). The negative pressure drainage time of patients in research group (13.6 ± 3.3 d vs.19.2 ± 4.2 d,t=8.744)was significantly lower than the control group(P<0.05).The culture positive rate of patients in research group[6.1%(4/66)d vs.18.2%(12/66),χ 2=4.552]was significantly lower than the control group(P<0.05).The rate of complications of patients in control group[18.2%(12/66)vs.4.6%(3/66),χ 2=6.092] was significantly higher than the research group (P<0.05). The relapse rate of patients in control group [21.8% (12/55)vs.7.9%(5/63),χ 2=4.589]was significantly higher than the research group(P<0.05).Conclusions The Zhuanggu-Huoxue-Buyang decoction combined with negative pressure seal flushing drainage treatment improves clinical indicators and reduces the incidence of complications and the recurrence rate.
