Influencing factors for the therapeutic effect of direct-acting antiviral agents in hepatitis C
10.3969/j.issn.1001-5256.2017.11.034
- VernacularTitle:直接抗病毒药物对丙型肝炎治疗效果的影响因素
- Author:
Dandan BIAN
1
;
Sujun ZHENG
Author Information
1. 首都医科大学附属北京佑安医院人工肝中心
- Keywords:
hepatitis C;
antiviral agents;
review
- From:
Journal of Clinical Hepatology
2017;33(11):2205-2208
- CountryChina
- Language:Chinese
-
Abstract:
The application of direct-acting antiviral agents significantly increases the rate of sustained virologic response in patients with hepatitis C,but there are still some patients who have no response during treatment or experience recurrence after treatment.Related influencing factors are research hotspots at present.This article reviews the influencing factors for the therapeutic effect of direct-acting antiviral agents in hepatitis C from the perspectives of HCV resistance-related mutations,HCV genotypes,viral load,degree of liver lesions,and drug combination,in order to provide a reference for clinical prevention and treatment of chronic hepatitis C.
