Research progresses on exosomes in glioma
10.3969/j.issn.1001-6325.2017.12.021
- VernacularTitle:外排体在脑胶质瘤中的研究进展
- Author:
hao Zi WANG
1
;
Lu GAO
;
peng Xiao GUO
;
Bing XING
Author Information
1. 中国医学科学院北京协和医学院北京协和医院神经外科
- Keywords:
glioma;
exosomes;
biomarkers;
liquid biopsy
- From:
Basic & Clinical Medicine
2017;37(12):1761-1764
- CountryChina
- Language:Chinese
-
Abstract:
Exosome is a kind of functional vesicles secreted to the extracellular matrix .The role of glioma exosomes in the development , diagnosis and treatment of glioma is increasingly recognized .This review aims to summarize the most common biomarkers of glioma exosomes and the applications of exosomes in treatments , which mainly includes mediating immune therapy , anti-tumor therapeutic vehicles , and intervention of intercellular communications in tumor cells.