Research progress of the correlation of Sox 5 and tumor
10.3969/j.issn.1001-6325.2017.12.022
- VernacularTitle:Sox5与肿瘤的相关性研究进展
- Author:
dong Guo SONG
1
;
jie Yuan NIU
Author Information
1. 天津医科大学第二医院胃肠外科
- Keywords:
Sox family;
Sox5;
cell differentiation;
tumor metastasis
- From:
Basic & Clinical Medicine
2017;37(12):1765-1769
- CountryChina
- Language:Chinese
-
Abstract:
Sox5 gene is located on 12p12.1 containing 29 exons.The gene can transcript 5 variants, thus produce 5 isoforms.L-SOX5A is an isoform with multiple functions , include regulate embryonic development , and determine cell differentiation .Sox5 also plays a role in pathogenesis of prostate cancer , breast cancer and lymphoma .
