Recent updates on neoadjuvant chemotherapy for advanced gallbladder cancer
10.3760/cma.j.issn.1007-8118.2017.11.017
- VernacularTitle:进展期胆囊癌新辅助化疗研究进展
- Author:
Qianglao MENG
1
;
Lin WANG
;
Zhimin GENG
Author Information
1. 710061,西安交通大学第一附属医院肝胆外科
- Keywords:
Gallbladder cancer;
Chemotherapy;
Neoadjuvant chemotherapy
- From:
Chinese Journal of Hepatobiliary Surgery
2017;23(11):789-792
- CountryChina
- Language:Chinese
-
Abstract:
Radical resection has been the only thempeutic method that can improve the long-term survival for patients with gallbladder cancer (GBC) so far.However,for advanced GBC,patients generally have poor prognosis due to late awareness of the disease and poor surgical resection rate.Sometimes,the neoadjuvant chemotherapy can downstage tumors for potential surgery thus increases the R0 resection rate,as confirmed in esophageal carcinoma,gastric carcinoma,colorectal carcinoma,and so on.Currently,the neoadjuvant chemotherapy in GBC has not been extensively performed.In this article,we will review the recent progression,current status,and effectiveness of associated regimens of chemotherapy treatment of GBC,as well as discussing the feasibility of delivering neoadjuvant chemotherapy to the patients with advanced GBC and solutions to major issues.
