Literature Analysis of 185 Cases of ADR Induced by Xianling Gubao Capsule

VernacularTitle:仙灵骨葆胶囊致不良反应185例文献分析
Author: Qian DU ¹ ; Zhe WANG ; Nairu YUN ; Yuhong HUANG ; Qiang XU ; Baohe WANG
Author Information

1. 天津中医药大学研究生院
Keywords: Xianling gubao capsule; ADR; Literature analysis; Rational drug use
From: China Pharmacy 2017;28(27):3785-3787
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To investigate the regularity and characteristics of adverse drug reactions (ADR) induced by Xianling gubao capsule,and to provide reference for rational drug use in the clinic.METHODS:ADR induced by Xianling gubao capsule were retrieved from CJFD,CBM,Wanfang database,VIP during Jan.2007-Oct.2016.The related information of 185 ADR cases were statistically analyzed.RESULTS:Among 185 patients,primary disease was mainly osteoporosis (63 cases,34.05％).The incidence of ADR induced by drug combination (70.81％) was higher than single drug (29.19％).ADR mostly occurred within 90 d after medication (67.03％).Main clinical manifestation was digestive system damage (82.68％).Most patients (61.62％) did not need treatment,symptomatic treatment or drug withdrawal to relieve ADR symptoms.CONCLUSIONS:The monitoring for ADR induced by Xianling gubao capsule should be strengthened in clinic,especially for ADR of liver fuction,soas to promote rational drug use.