The 458th case: fever, cytopenia, abdominal pain, and multiple intestinal ulcerations with perforation
10.3760/cma.j.issn.0578-1426.2017.10.020
- VernacularTitle:第458例——发热、血细胞减少、腹痛、多发肠道溃疡穿孔
- Author:
Yan LIN
1
;
Honghu XIE
;
Wei ZHAO
;
Min WU
;
Weiying GU
Author Information
1. 常州市第一人民医院血液科
- Keywords:
Myelodysplastic syndromes;
Beh(c)et's disease
- From:
Chinese Journal of Internal Medicine
2017;56(10):789-792
- CountryChina
- Language:Chinese
-
Abstract:
Trisomy 8 in myelodysplastic syndrome (MDS) plays an important role in concurrent intestinal Beh?et's disease (BD) pathogenesis.Here,we reported a case of intestinal BD combined with MDS involving trisomy 8.A 48-year-old woman who has had a 20-year history of recurrent oral ulcer,perineal ulcer and iris,was diagnosed as MDS with trisomy 8 four years ago.She developed high fever and acute abdominal pain.Multiple ulcerative perforations in ileum and colon were found by endoscopy,meeting the criteria for intestinal BD.The patient was successfully treated with immunomodulatory drugs.
