Long noncoding RNA in atherosclerosis
10.3760/cma.j.issn.1001-4497.2017.08.015
- VernacularTitle:长链非编码RNA(lncRNA)与动脉粥样硬化性疾病的研究进展
- Author:
Feng QIN
1
;
Zhiqing ZHAO
;
Jian ZHOU
;
Zaiping JING
Author Information
1. 200433,上海第二军医大学附属长海医院血管外科
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2017;33(8):508-512
- CountryChina
- Language:Chinese
-
Abstract:
Long noncoding RNA(IncRNA) represents a class of ＞200bp RNA genes that has no ability to code proteins.It was considered that IncRNA is "junk RNA" which have no function over the last couple of decades.However,an increasing number of studies have found that lncRNA play distinct biologic functions by particular mechanisms.Because the incidence rate and mortality rate of atherosclerosis is very high,people always pay a lot of attention on it.But lncRNA studies in atherosclerosis are just beginning.lncRNA may be a key target in the progression of atherosclerosis and may become a novel therapeutic target to prevent,diagnose and treat this disease.
