The contrastive study of the short-term efficacy of compound gargle solution chlorhexidine giuconatie and kangfuxin liquid in treatment of recurrent aphthous ulcer
10.3760/cma.j.issn.1008-1372.2017.09.006
- VernacularTitle:复方氯己定含漱液和康复新液治疗复发性阿弗他溃疡的短期临床疗效对比研究
- Author:
Sheng GE
1
;
Ning DUAN
;
Yuefeng SONG
;
Fan HUANG
;
Xiang WANG
;
Hongliu JIANG
;
Wenmei WANG
Author Information
1. 南京大学医学院附属口腔医院(南京市口腔医院)口腔黏膜病科
- Keywords:
Chlorhexidine/TU;
ANTI-ULCER AGENTS (TCD)/TU;
Oral ulcer/DT/ZD
- From:
Journal of Chinese Physician
2017;19(9):1302-1304,1308
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the short-term efficacy of compound gargle solution chlorhexidine giuconatie and kangfuxin liquid in treatment of recurrent aphthous ulcer (RAU).Methods Eighty patients clinically diagnosed with RAU were chosen and randomly divided into two groups.Test group 1 (40 cases) and Test group 2 (40 cases) were treated with compound gargle solution chlorhexidine giuconatie and kangfuxin liquid respectively until ulcer has been healed completely to evaluate the difference of two groups in clinical efficacy.Return visit and follow-up visit were conducted 7 days and 30 days after the initial treatment,respectively.Results The analgesic onset time of Test group 1 [(6.24 ± 1.09) min] was shorter than that of Test group 2 [(8.62 ± 1.04) min],with statistically significant difference (P ＜ 0.01).The analgesic maintenance time of Test group 1 [(29.47 ± 3.45) min] was longer than that of Test group 2 [(21.61 ±2.18) min],with statistically significant difference (all P ＜ 0.01).The duration of ulcer of Test groups 1 and 2 was (5.97-± 0.87)days and (4.76 ± 1.14)days,with statistically significant difference (P ＜0.01).Conclusions Compound gargle solution chlorhexidine giuconatie and kangfuxin liquid both have a certain level of clinical efficacy for RAU,with the former featuring shorter analgesic onset time and longer duration and the latter advantageous in promoting RAU healing short-term usage of compound gargle solution chlorhexidine giuconatie and kangfuxin liquid cannot prolong RAU dormancy.
