The application of endoscopic ultrasound-guided needle-based confocal laser endomicroscopy in diagnosis of pancreatic neoplasms
10.3760/cma.j.issn.1007-5232.2017.08.003
- VernacularTitle:内镜超声引导下细针型共聚焦显微内镜检查在胰腺肿瘤诊断中的初步应用
- Author:
Yang DI
1
;
Sijie HAO
;
Weijia XU
;
Yun BAO
;
Feng TANG
;
Deliang FU
;
Chen JIN
;
Liang ZHONG
Author Information
1. 复旦大学附属华山医院胰腺外科 复旦大学胰腺病研究所
- Keywords:
Pancreatic neoplasms;
Diagnosis;
Ultrasonography;
Confocal laser endomicroscopy
- From:
Chinese Journal of Digestive Endoscopy
2017;34(8):549-553
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the application of endoscopic ultrasound-guided needle-based confocal laser endomicroscopy ( EUS-nCLE) in the diagnosis of pancreatic neoplasms. Methods Patients with pancreatic neoplasms were diagnosed by endoscopic ultrasonography and punctured by 19 G needle, and then the confocal microprobe was implanted through the needle. The lesions nature was estimated according to obtained images. The diagnostic yield and complication was evaluated and compared with pathology. Results A total of 28 patients successfully underwent EUS-nCLE, and high quality images were obtained in all patients. The final diagnosis were 5 cases of serous cystadenoma ( SCN ) , 3 cases of mucinous cystadenoma, 3 cases of intraductal papillary mucinous neoplasms ( IPMN) , 1 case of pseudocyst, 10 cases of ductal adenocarcinoma, 1 case of neuroendocrine tumor, 2 cases of solid pseudopapillary tumor, 2 cases of chronic pancreatitis, and 1 cases of lymphoma. The diagnostic yield in 26 patients with pathology was 73. 1%(19/26) and the specificity of SCN and IPMN was 100%(7/7). The complications, mostly pancreatitis and intracystic hemorrhage, occurred in 10. 7% ( 3/28) patients. Conclusion EUS-nCLE is a safe and feasible method in the diagnosis of pancreatic neoplasms, and shows high specificity in SCN and IPMN.
