Clinical application of serum follicular statin 1 in the diagnosis of chronic heart failure
10.3969/j.issn.1673-4130.2017.20.005
- VernacularTitle:血清卵泡抑素样蛋白1在慢性心力衰竭患儿诊断中的应用研究
- Author:
Wei ZHANG
1
;
Yao BAI
;
Xiufen SHEN
Author Information
1. 昆明医科大学第二附属医院检验科
- Keywords:
serum follicular statin 1;
chronic heart failure;
children;
diagnosis
- From:
International Journal of Laboratory Medicine
2017;38(20):2813-2815
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the application value of serum follicular statin 1(FSTL-1) in the diagnosis of chronic heart fail-ure(CHF) .Methods A total of 60 CHF children treated from January 2013 to January 2016 in hospital were selected as observa-tion group .According to New York Heart Association (HYHA) ,the subjects were divided into Type Ⅱ group ,Type Ⅲ group and Type Ⅳ group ,20 cases in each group .In addition ,60 healthy children were selected as control group .FSTL-1 ,NT-proBNP and LVMI were detected and analyzed .Results FSTL-1 ,NT-proBNP and LVMI in Type Ⅱ group ,Type Ⅲ group and Type Ⅳ group were higher than those of control group(P< 0 .05) .As the grade of cardiac function increasing ,FSTL-1 ,NT-proBNP and LVMI were higher(P<0 .05) .FSTL-1 had positive correlations with NT-proBNP and LVMI .The positive rate of FSTL-1 for diagnosis CHF was 96 .67% ,which had no significant difference with gold standard (P>0 .05) .Conclusion With the progress of illness ,the level of FSTL-1 increases ,which is importance in the diagnosis and monitoring of CHF .It is worthy of further application and pro-motion in clinical practices .
