Distribution and drug resistant status of bacterium extended spectrum beta lactamases in sputum samples from patients with lower respiratory tract infection
10.3969/j.issn.1673-4130.2017.20.013
- VernacularTitle:下呼吸道感染患者痰标本中产ESBLs菌株的分布及耐药情况
- Author:
Shirong LUO
1
;
Weidong TANG
;
Xubin TAN
;
Tao FENG
;
Luping YANG
;
Li ZHOU
Author Information
1. 攀枝花市中西医结合医院检验科
- Keywords:
lower respiratory tract;
extended spectrum beta lactamases;
drug resistance;
distribution
- From:
International Journal of Laboratory Medicine
2017;38(20):2835-2836,2839
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the distribution of bacterium extended spectrum beta lactamases (ESBLs) in sputum samples from patients with lower respiratory tract infection in Panzhihua Hospital of Integrated Traditional Chinese and Western Medicine . Methods A total of 512 strains of gram negative bacterium were isolated from sputum samples of patients with lower respiratory tract infection from January 2014to January 2016 ,standard disk diffusion method was used to detected ESBLs ,drug sensitivity was performed by K-B disk diffusion method .Distribution and drug resistant status of ESBLs bacterium were analyzed .Results Detec-tion rate of ESBLs bacteriumin cadre ward and ICU were higher than that in department of respiration ,and the difference was sta-tistical significant(P< 0 .01) .Among ESBLs bacterium isolated from department of respiration ,Escherichia coli accounted for 37 .5% ,Enterobacter cloacae accounted for 25 .8% .Among ESBLs bacterium isolated from cadre ward ,Escherichia coli accounted for 58 .2% ,Enterobacter cloacae accounted for 45 .5% .The resistant rate of gram negative bacterium producing ESBLs to trime-thoprim was lowest .Conclusion It′s important to understand the distribution and drug resistant status of gram negative bacterium , so as to provide the basis for rational use of antibiotics .
