Advances in Study on Role of Circular RNA in Digestive System Neoplasms
10.3969/j.issn.1008-7125.2017.10.011
- VernacularTitle:环状RNA在消化系统肿瘤中作用的研究进展
- Author:
Genwen CHEN
1
;
Jianyong SUN
Author Information
1. 复旦大学附属中山医院消化内科 200032
- Keywords:
Circular RNA;
Digestive System Neoplasms;
Biological Markers;
Diagnosis
- From:
Chinese Journal of Gastroenterology
2017;22(10):627-629
- CountryChina
- Language:Chinese
-
Abstract:
Circular RNA (circRNA),a class of non-coding RNA (ncRNA),widely exists in various kinds of cells. CircRNA is highly conserved in different species and can act as a miRNA sponge to regulate gene expression. More and more studies showed that circRNA plays an important role in pathogenesis and development of digestive system neoplasms, and can be used as a biomarker for diagnosis and prediction of prognosis. However,its function still needs further research to verify. This article reviewed the advances in study on role of circRNA in digestive system neoplasms.
