Role of Th17 Cells in Pathogenesis of Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2017.10.012
- VernacularTitle:Th17细胞在炎症性肠病发病中的作用
- Author:
Jing MA
1
;
Dafan CHEN
;
Xinjian WAN
Author Information
1. 上海交通大学附属第一人民医院消化科 200080
- Keywords:
Inflammatory Bowel Disease;
Crohn Disease;
Colitis;
Ulcerative;
Th17 Cells;
Interleukin-17
- From:
Chinese Journal of Gastroenterology
2017;22(10):630-633
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease (IBD)is a chronic inflammatory disease of the digestive tract,including Crohn's disease (CD)and ulcerative colitis (UC). The cause and pathogenesis of IBD is not fully clear,and the disorder of immune function plays a key role in the pathogenesis of IBD. Th17 cells are CD4 + T cells that can specifically produce IL-17. Recent studies have demonstrated that Th17 cells play an important role in the abnormal immune response of IBD. This article reviewed the role of Th17 cells in the pathogenesis of IBD.
