Preliminary study on quantitative assessment of nonalcoholic fatty liver disease by MRI
10.7687/j.issn1003-8868.2017.07.063
- VernacularTitle:磁共振对非酒精性脂肪肝定量诊断的初步研究
- Author:
ming Zi YIN
1
;
jun Jian SHI
;
yan Qiu XU
;
yong Zhi WU
Author Information
1. 北京市门头沟区医院影像中心
- Keywords:
diffusion weighted imaging;
magnetic resonance spectroscopy;
fatty liver;
magnetic resonance imaging
- From:
Chinese Medical Equipment Journal
2017;38(7):63-66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the feasibility for quantitative assessment of nonalcoholic fatty liver disease by sequence of diffusion weighted imaging and hydrogen proton magnetic resonance spectroscopy.Methods Thirty patients with NAFLD and twenty-six normal volunteers were enrolled in an experiment group,and 25 healthy volunteers were selected into a control group.All the patients and volunteers underwent CT and MRI examinations.With the ratio of liver-to-spleen CT value as reference standard,the correlation and difference of ADC value,value of water peak,the area under water peak,values of lipid peak and area under lipid peak and fat fraction were measured and compared between the two groups.Results There was positive significant correlation between ratio of liver-to-spleen CT value and ADC value (r=0.92,P＜0.05),and negative significant correlation between ratio of liver-to-spleen CT value and lipid peak and area of lipid peak (r=-0.91 and r=-0.96,respectively;all P＜0.05),there was significant negative correlation between ADC value and lipid peak and area of lipid peak (r=-0.91,P＜0.05),and ADC value,the values of water peak,lipid peak and area under peak and fat fraction were different between the two groups (P＜0.05).Conclusion There is significant correlation and difference between DWI and 1H-MRS in evaluating NAFLD,which has the potential to quantitatively diagnose the severity and degree of fatty liver.
