Cancer incidence in patients with type 2 diabetes mellitus in Minhang District of Shanghai
10.3969/j.issn.1672-8467.2017.05.004
- VernacularTitle:上海市闵行区2型糖尿病患者恶性肿瘤的发病状况分析
- Author:
lin Hui XU
1
;
jie Yu YAN
;
Hong FANG
;
dong Bao YAO
;
you Guo QIN
;
hong Wang XU
;
Fen ZHANG
;
Qi GUO
;
yan Jun WANG
;
Dong-li YUAN
;
XU FANG
Author Information
1. 上海市闵行区疾病预防控制中心 上海 201101
- Keywords:
type 2 diabetes mellitus;
malignant tumor;
incidence;
retrospective cohort study
- From:
Fudan University Journal of Medical Sciences
2017;44(5):574-579
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk of overall and site-specific cancers in Chinese patients with type 2 diabetes mellitus (T2DM) in Minhang District of Shanghai.Methods A population-based retrospective cohort study including 51 372 T2DM patients was conducted in Minhang District,Shanghai from 2004 to 2014.All T2DM patients were enrolled from the standardized management system based on local electronic information system of Shanghai.Newly-diagnosed cancer cases were identified by record-linkage with the Shanghai Cancer Registry.Standardized incidence ratios (SIR) and 95％CI were used to estimate the risk of cancers among T2DM patients.Results Overall crude incidence rate (CIR) of cancers was 969.69 per 105 person-years in men and 834.17 per 105 person-years in women.The age-standardized rate (ASR [W]) was 206.72 per 105 person-years in men and 285.80 per 105 person-years in women.Increased risk of cancer was found in both sex,with an SIR of 0.93 (95％CI:0.88-0.98) in men and 1.07 (95％ CI:1.01-1.12) in women.Conclusions Our results indicate that patients with T2DM may have an increased risk of some cancers,and the increase may vary by sub-sites of cancers.
