Acoustic radiation force impulse imaging in preoperative assessment of liver cirrhosis in infants with biliary atresia
10.13929/j.1003-3289.201701064
- VernacularTitle:声辐射力脉冲成像技术术前评估胆道闭锁患儿肝硬化
- Author:
Jun JIANG
1
;
Fen GAO
;
Yaqing CHEN
;
Jing FANG
;
Luan LI
;
Xiaoying WANG
;
Shengli GU
Author Information
1. 上海交通大学医学院附属新华医院超声科
- Keywords:
Acoustic radiation force impulse imaging;
Cirrhosis;
Biliary atresia;
Infant
- From:
Chinese Journal of Medical Imaging Technology
2017;33(10):1522-1525
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic performance of acoustic radiation force impulse (ARFI) imaging in assessing liver cirrhosis preoperatively in infants with biliary atresia (BA).Methods A total of 64 consecutive infants with BA who underwent ARFI imaging in 3 days before Kasai surgery were recruited.Virtual Touch Quantification mode was used to measure shear wave speed (SWS),All infants with BA underwent liver biopsy during the surgery.The mean SWS of infants with and without liver cirrhosis were compared and analyzed.The diagnostic efficacy of SWS was observed using ROC curves.Results Liver cirrhosis was found in 8 of 64 infants.The mean SWS in infants with cirrhosis was significant-ly higher than that in infants without cirrhosis ([2.51±0.50]m/s vs [1.74±0.31]m/s,t=6.039,P＜0.001).The cutoff value of SWS for predicting liver cirrhosis was 2.16 m/s,the area under ROC curve was 0.930 (P＜0.001),and the diagnostc sensitivity and specificity was 87.50％ and 92.86％,respectively.Conclusion ARFI imaging is helpful to predic tion of liver cirrhosis in infants with BA preoperatively.It may be an effective method for clinical management and prognosis prediction in infants with BA.
