Study on application of serum immunoglobulin and CRP levels and lung function detection in diagnosis and treatment of RMPP
10.3969/j.issn.1671-8348.2017.27.024
- VernacularTitle:血清Ig、CRP联合肺功能检测在RMPP诊治中的应用
- Author:
Wei XIONG
1
;
Ke QIAN
;
Jian WU
Author Information
1. 重庆市酉阳县人民医院儿科 409800
- Keywords:
immunoglobulin;
C reactive protein;
children;
refractory mycoplasma pneumoniae pneumonia;
lung function
- From:
Chongqing Medicine
2017;46(27):3822-3824
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of serum immunoglobulin(Ig) and C-reactive protein(CRP) and lung function detection in the diagnosis and treatment of child refractory mycoplasma pneumoniae pneumonia(RMPP).Methods Eighty-two cases of child RMPP treated in these 3 hospitals from January 2015 to June 2016 were selected as the pneumonia group and contemporaneous 30 baseline data matched children undergoing physical examination served as the control group.The levels of serum IgA,IgG,IgM,IgE and CRP,forced expiratory volume at 1 s (FEV1),forced vital capacity (FVC) and other pulmonary function indexes were compared between the two groups.Their application value in diagnosis was analyzed.Results Compared with the control group,serum IgA and IgG levels,FEV1 and FVC in the pneumonia group were decreased,while serum IgE and CRP levels were increased (P＜0.05).Compared with before treatment,serum IgA and IgG levels,FEV1 and FVC after treatment in the pneumonia group were increased,while serum IgE and CRP levels were decreased(P＜0.05).Serum IgA and IgG levels,FEV1 and FVC before and after treatment in the ineffective cases of the pneumonia group were lower than those in the effective cases,while serum IgE and CRP levels were higher than those in the effective cases (P＜0.05).Serum IgA,IgG,IgE and CRP levels in children cases of RMPP were related to FEV1 arnd FVC level and treatment effective rate.Conclusion Serum IG,CRP and lung function detection has larger application value in diagnosing child RMPP and is worth clinical promotion.
