Study on 18F-FDG PET/CT imaging features of thoracolumbar tuberculosis
10.3969/j.issn.1671-8348.2017.26.024
- VernacularTitle:胸腰椎体结核的18F-FDG PET/CT影像特点研究
- Author:
Beibei TAN
1
;
Jinglan GUO
Author Information
1. 西南医科大学附属医院核医学科
- Keywords:
positron-emission tomography;
thoracolumbar tuberculosis;
tomography;
differential diagnosis
- From:
Chongqing Medicine
2017;46(26):3668-3670
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the 18F-FDG PET/CT imaging features of thoracolumbar tuberculosis.Methods Nine-ty-eight patients with thoracolumbar vertebral column destruction receiving 18F-FDG PET/CT examination in our hospital from May 2005 to January 2017 were selected as the study subjects and divided into the tuberculosis(TB) group (n=27) and non-TB group (n=71) according to the result of pathology examination and follow-up.The 18F-FDG PET/CT signs were compared between the two groups,and the binary classification Logistic regression was used to screen out the signs with statistical significance.Results Forty-two lesions and 114 lesions were detected in the TB group and non-TB group respectively.The incidence rates of continuous vertebral body involvement,intervertebral disc lesion,vertebral body compression fractures,cold abscess," radioactive cold area",high lesion SUVmax and slightly higher SUVmax sign in the TB group were higher than those in the non-TB group(P＜ 0.05) The binary classification Logistic regression analysis results showed that continuous vertebral involvement,intervertebral disc lesion,vertebral body compression fractures,cold abscess and "radioactive cold area" were the independent factors for diagnosis of thoracolumbar TB(P＜0.05).The sensitivity,specificity,positive prediction value,negative predictionvalue and Youden index in the combination of continuous vertebral involvement + intervertebral disc lesion were 71.4％,81.6％,58.8％,88.6％,53.0％,respectively.Conclusion For the diagnosis of thoracolumbar TB,the combination of continuous vertebral involvement + intervertebral disc lesion has the highest diagnostic value.
