Advances in the relationship between peritoneal microenvironment and peritoneal me-tastasis in colorectal cancer
10.3969/j.issn.1000-8179.2017.17.054
- VernacularTitle:腹腔微环境与结直肠癌腹膜转移关系的研究进展
- Author:
YANG CHAO
1
;
XIAO KUANG
;
SONG DAN
;
TONG SHILUN
Author Information
1. 武汉大学人民医院胃肠外科 武汉市430060
- Keywords:
colorectal cancer;
peritoneal metastasis;
peritoneal microenvironment;
cells
- From:
Chinese Journal of Clinical Oncology
2017;44(17):894-898
- CountryChina
- Language:Chinese
-
Abstract:
Peritoneal metastasis is very common in colorectal cancer and often indicates bad prognosis. The peritoneum, which con-tains an abundant supply of blood and specific types of resident and migrating cells, lines the surface of the abdominal wall and covers the abdominal organs. The combination of cells, extracellular matrix, and local unique physicochemical composition of the abdominal cavity provide a complex and relatively stable peritoneal microenvironment. The cells in this environment can be induced by cancer cells to be involved in tumor growth, invasion, and peritoneal metastasis. This review summarizes the major cellular components in-volved in the peritoneal microenvironment.
