Research progress of tumor necrosis factor- α induced protein 8 family

VernacularTitle:肿瘤坏死因子α诱导蛋白8家族的研究进展
Author: Min ZHAI ¹ ; Zhongsong MAN ; Zhongwei ZHU ; Jin ZHOU ; Haitao ZHANG
Author Information

1. 215000,苏州大学附属第一医院普外科
Keywords: Tumor necrosis factor-α; Biology; Review; Induced protein 8
From: Chinese Journal of Postgraduates of Medicine 2017;40(10):954-957
CountryChina
Language:Chinese
Abstract: Tumor necrosis factor-α induced protein 8 family is a group of newly discovered proteins induced by tumor necrosis factor-α. This protein family owns four highly homologous members:TIPE, TIPE1, TIPE2, TIPE3. With the deepening of the research, we found that TNFAIP8 family plays an important role in cell apoptosis, signal transduction, invasion and metastasis of tumor cell proliferation. This paper reviews the structure, mechanism, and biological function of the TNFAIP8 family.