Preliminary study on serum pharmacochemistry of Shijing pill
10.3760/cma.j.issn.1673-4246.2017.10.013
- VernacularTitle:十精丸血清药物化学研究
- Author:
Rui YANG
1
;
Delong ZOU
;
Lijuan CHEN
Author Information
1. 黑龙江中医药大学研究生学院
- Keywords:
DNA Fingerprinting;
Shijing pill;
Transitional constituents
- From:
International Journal of Traditional Chinese Medicine
2017;39(10):914-918
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct serum pharmacochemistry study onShijing pill. Methods HPLC fingerprints of serum in rats after takingShijingpill were established,the serun samples after takingShijing pill, decoction without one of the component drugs and single crude drug were compared,the transitional constituents absorbed into the blood and the original crude after takingShijing pill was determined.Results Fourteen transitional constituents were detected in rat blood after takingShijing pill,four of which were permanent component of blood,seven of which were prototype constituents,three of which were metabolites. Conclusions Some of chemical composition ofShijing pill was clarified preliminarily,that contributes to further studying pharmacodynamic meterial foundation ofShijing pill.